|
|
21 Sep 2021, 8:22
|
|
Do you want to meet Prof. Vera Gorbunova?
This message is sent on behalf of Maria Metsger.
Dear colleagues,
this week, I am hosting Prof. Vera Gorbunova from the University of Rochester, USA. She will give a lecture at MU Life Sciences Seminar on Thursday, 23.09. Vera is a Doris Johns Cherry Professor of Biology and Medicine Co-director Rochester Aging Research Center.
Her research is focused on understanding the mechanisms of longevity and genome stability and on the studies of exceptionally long-lived mammals. Prof. Gorbunova pioneered comparative biology approach to study aging and identified rules that control the evolution of tumor suppressor mechanisms depending on the species lifespan and body mass.
Prof. Gorbunova also investigates the role of Sirtuin proteins in maintaining genome stability. More recently the focus of her research has been on the longest-lived rodent species the naked mole rats and the blind mole rat. Prof. Gorbunova identified high molecular weight hyaluronan as the key mediator of cancer-resistance in the naked mole rat.
See more information at Prof. Gorbunova´s research group website.
Please let me know if you are interested in meeting Vera for discussions on Thursday 23th of September during the day or if you want to join for informal dinner on Thursday evening.
With best regards
Maria Metsger
maria.metsger@ceitec.muni.cz
|
|
|
Some of Prof. Vera Gorbunova´s publications:
- Tian X, Firsanov D, Zhang Z, Cheng Y, Luo L, Tombline G, Tan R, Simon M, Henderson S, Steffan J, Goldfarb A, Tam J, Zheng K, Cornwell A, Johnson A, Yang JN, Mao Z, Manta B, Dang W, Zhang Z, Vijg J, Wolfe A, Moody K, Kennedy BK, Bohmann D, Gladyshev VN, Seluanov A, Gorbunova V. SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species. Cell. 2019 Apr 18;177(3):622-638
PubMed link
- Zhao J, Tian X, Zhu Y, Zhang Z, Rydkina E, Yuan Y, Zhang H, Roy B, Cornwell A, Nevo E, Shang X, Huang R, Kristiansen K, Seluanov A, Fang X, Gorbunova V. Transformation of naked mole-rat cells. Nature 2020 Jul;583(7814):E8-E13. doi: 10.1038/s41586-020-2411-9.PMID: 32612220Free PMC article. PubMed Link
- Seluanov A, Gladyshev VN, Vijg J, Gorbunova V. (2018). Mechanisms of cancer resistance in long lived mammals. Nat Rev Cancer. 2018 Jul;18(7):433-441.
PubMed link
- Tian, X., Azpurua, J., Hine, C., Vaidya, A., Myakishev-Rempel, M., Ablaeva, J., Mao, Z., Nevo, E., Gorbunova, V., and Seluanov, A. (2013). High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat. Nature 499, 346-349.
PubMed link
|
|
|
|
|
|
|
