Lecture will be held in English

Hosted by

Dáša Bohačiaková

About the lecture

Using Stem Cell Models To Help Understand Dementia

In his work he uses induced pluripotent stem cells (iPSCs) to help understand the earliest, underlying causes of dementia. Working with skin cell donations from people who have inherited forms of dementia, I generate human, patient-derived brain cells in a dish. By generating neurons, astrocytes and microglia, my work aims to understand the interplay between the toxic amyloid proteins that accumulate in disease and brain inflammation. I will present some recent work on familial Alzheimer’s disease as well as a very rare dementia called familial British dementia, implicating the immune system in the onset of dementia.
What changes in the brain to bring about the onset of dementia? Why does it take many decades for the disease to manifest? Can we find ways to delay the onset of symptoms and improve the lives of people affected by dementia?

Registration for lunch with the speaker /for Ph.D. students/

The sponsored lunch usually takes place in the Campus River restaurant. Please meet the speaker and other students at 12:45 at the reception desk at the main entrance (building B22, see the map below).