Dr. Victor Tybulewicz
Francis Crick Institute, London, UK
My group is interested in signal transduction in B and T cells, from the antigen, chemokine and cytokine receptors, as well as integrins. Signals from these receptors play critical roles in B and T cell development, activation, migration, survival and death.
We are studying how signalling pathways control these processes, using mouse genetics, protein biochemistry, imaging, cell biology, and RNAi and CRISPR screens. Current research interests include pathways controlling B and T cell migration and adhesion, B cell survival, the biology of memory B cells and the function of long non-coding RNAs in lymphocyte biology.