Regulation of Mammalian Transcription: Insights from Cryo-EM

  • 11 May 2023
    4:00 PM
  • University Campus Bohunice (pavilion B11/ seminar room 132)

Lecture will be held in English


Hosted by

Richard Štefl

About the lecture

RNA polymerase (Pol) II is a multisubunit enzyme that produces mRNA during transcription of protein-coding genes. Its activity is highly regulated by both protein and RNA factors. In this talk, I will discuss how we have been using cryo-EM and biochemistry to gain insights into the structures, conformations, and activities of mammalian Pol II complexes.


Registration for lunch with the speaker /for Ph.D. students/

The sponsored lunch usually takes place in the Campus River restaurant. Please meet the speaker and other students at 12:45 at the reception desk at the main entrance (building B22, see the map below).


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