Rewiring DNA Repair for Genome Stability or Genome Haploidization
30 March 2023
- University Campus Bohunice (pavilion B11/ seminar room 132)
Lecture will be held in English
About the lecture
Homologous recombination fulfils fundamental DNA repair roles during mitotic proliferation as well as during meiosis. Crucially, however, context-specific modifications tailor the recombination machinery to avoid, or enforce, formation of reciprocal exchanges – crossovers – between maternal and paternal chromosomes. I will discuss how cells rewire the function of various DNA repair enzymes to regulate crossing-over and either safeguard genome stability (mitosis) or promote genetic diversity (meiosis).
Registration for lunch with the speaker /for Ph.D. students/
The sponsored lunch usually takes place in the Campus River restaurant. Please meet the speaker and other students at 12:45 at the reception desk at the main entrance (building B22, see the map below).