Rewiring DNA Repair for Genome Stability or Genome Haploidization

  • 30 March 2023
    4:00 PM
  • University Campus Bohunice (pavilion B11/ seminar room 132)

Lecture will be held in English


Hosted by

Lumír Krejčí

About the lecture

Homologous recombination fulfils fundamental DNA repair roles during mitotic proliferation as well as during meiosis. Crucially, however, context-specific modifications tailor the recombination machinery to avoid, or enforce, formation of reciprocal exchanges – crossovers – between maternal and paternal chromosomes. I will discuss how cells rewire the function of various DNA repair enzymes to regulate crossing-over and either safeguard genome stability (mitosis) or promote genetic diversity (meiosis).


Registration for lunch with the speaker /for Ph.D. students/

The sponsored lunch usually takes place in the Campus River restaurant. Please meet the speaker and other students at 12:45 at the reception desk at the main entrance (building B22, see the map below).


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