Dear Students,

You are cordially invited to the lecture of MU Life Sciences Seminar:

„Base-Modified Nucleic Acids for Applications in Diagnostics or Chemical Biology”
by Prof. Michal Hocek, Institute of Organic Chemistry and Biochemistry ASCR, v.v.i., Czech Republic

WHEN: Thursday, October 21th 2021 at 4 p.m.
WHERE: Seminar room 132, pavilion B11, University Campus Bohunice

The announcement is published also at

https://seminarseries.muni.cz/life-sciences/lectures/michal-hocek

PhD students who would like to attend a sponsored lunch with Prof. Hocek (Thursday, at 13:00 at Campus River) please register by Wednesday October 20th, using the form at the website above.

With best regards,
Lucie Nesvadbová
MU LSS administrator
lus@sci.muni.cz

About the lecture

The talk will summarize our most recent findings in development of new methods of synthesis of modified nucleoside triphosphates and enzymatic synthesis of base-modified nucleic acids (DNA or RNA) through polymerase incorporation of the modified nucleotides. The modified nucleic acids are applied in diagnostics (environment-sensitive fluorescent labelling, redox labelling etc.) and chemical biology (bioconjugations, cross-linking with proteins, regulation of protein-DNA binding and switching transcription).